For men hair loss issue, around 80 to 90 % is classified as Androgenetic Alopecia (AGA) .Androgenetic Alopecia (AGA) is a classical case of hair loss resulting from the imbalance of androgens. AGA is the transformation of testosterone to dihydrotestosterone (DHT) — a ‘faulty’ male hormone that instructs cells not to regenerate new hair.

Two types of 5α-reductase convert testosterone to DHT: *Type-I 5α-reductase, present in large quantity in sebaceous glands *Type-II 5α-reductase, present in large quantity in the hair papilla